Independent Studies



Saw Plametto 
(1) Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med. 2002 Apr;8(2):143-52; Erratum in J. Altern Complement Med. 2006 Mar; 12(2):199.

(2) Marks LS, Hess DL, Dorey FJ, Luz Macairan M, Cruz Santos PB, Tyler VE. Tissue effects of saw palmetto and finasteride: use of biopsy cores for in situ quantification of prostatic androgens. Urology. 2001 May;57(5):999-1005. http://www.ncbi.nlm.nih.gov/pubmed/11337315?dopt=Citation.

(3) Chen, W., Zouboulis, Ch.C., & Orfanos, E.E. 1996) the 5-reductase system and its inhibitors. Dermatology, 193, 177-184.

(4) Choudry, R., Hodgins, M.B., Van der Kwast, T.H., Brinkmann, A.O., & Boersma, W.J.A. (1992) Localization of androgen receptors in human skin by immunohistochemistry: implications for the hormonal regulation of hair growth, sebaceous glands and sweat glands. Journal of Endocrinology, 133 467-475.

(5) Dallob, A.L., Sadick, N.S., Unger, W., Lipert, S., Geissler, L.A., Gregoire, S.L., Nguyen, H.H., Moore, E.C., & Tanaka, W.K. (1994) The effect of finasteride, a 5-reductase inhibitor, on scalp skin testosterone and dihydrotestosterone concentrations in patients with male pattern baldness. Journal of Clinical Endocrinology and Metabolism, 79(3), 703-706.

(6) Sawaya, M.E., & Price, V.H. (1997). Different levels of 5 alpha reductase type I & II, aromatase, and androgen receptors in hair follicles of women and men with androgenetic alopecia. The Journal of Investigative Dermatology, 10(3), 296-300.

Fo-Ti Root 
(7) A Chinese study found that ‘Dang-Gui Decoction for Enriching the Blood’ (BE), a traditional fo-ti Chinese formulation, stimulates red blood cell production, which contributes to lush, healthy hair growth.

(8) Age Old Chinese Herb Fo-Ti is Widely Used to Restore Hair and Reverse Gray, Sunday, December 26, 2010 by Susan Laverie.
http://www.naturalnews.com/030837_Fo-Ti_hair_loss.html#ixzz27PO4QGcM.

(9) Myocardial protection against ischaemia-reperfusion injury by a Polygonum multiflorum extract supplemented ‘Dang-Gui decoction for enriching blood’, a compound formulation, ex vivo. Phytother Res. 2000 May;14(3):195-9.Yim TK, Wu WK, Pak WF, Mak DH, Liang SM, Ko KM.Department of Biochemistry, The Hong Kong University of Science & Technology, Clear Water Bay, Hong Kong, China.

MSM 
(10) The Effect of Methylsulfonylmethane on Hair Growth Promotion of Magnesium Ascorbyl Phosphate for the Treatment of Alopecia. Srinivasan SHANMUGAM, Rengarajan BASKARAN, Santhoshkumar NAGAYYA-SRIRAMAN, Chul-Soon YONG, Han-Gon CHOI, Jong Soo WOO, and Bong-Kyu YOO Biomolecules & Therapeutics July 2009 17(3): 241-248. Link

(11) College of Pharmacy, Yeungnam University, Kyungsan 712-749, Republic of Korea Parcell S. Sulfur in human nutrition and applications in medicine. Altern Med Rev. 2002 Feb;7(1):22-44.

Silica
(12) Effect of oral intake of choline-stabilized orthosilicic acid on hair tensile strength and morphology in women with fine hair. Wickett RR, Kossmann E, Barel A, Demeester N, Clarys P, Vanden Berghe D, Calomme M. Arch Dermatol Res. 2007 Dec;299(10):499-505. Epub 2007 Oct 25. College of Pharmacy, University of Cincinnati, Cincinnati, OH, http://www.ncbi.nlm.nih.gov/pubmed/17960402.

(13) PDR for Herbal Medicines, 2nd Edition; Joerg Gruenwald, PhD, 2000.

(14) Gale Encyclopedia of Alternative Medicine, Volume 2; Jacqueline L. Longe, 2005.

Ashwagandha 
(15) https://www.planetherbs.com/specific-herbs/ashwagandha-wonder-herb-of-india.html

(16) Bhattacharya S, Goel R, Kaur R, Ghosal S. Anti-stress activity of sitoindosides VII and VIII, new acylsterylglucosides from Withania somnifera. Phytother Res 1987;1:32–39.

(17) Grandhi A, Mujumdar AM, Patwardhan B. A comparative pharmacological investigation of Ashwagandha and Ginseng. J Ethnopharmacol 1994;44:131–5.

(18) K. Chandrasekhar, Jyoti Kapoor, and Sridhar Anishetty1. “A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults.” Indian J Psychol Med. 2012 Jul-Sep; 34(3): 255-262. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/

Pumpkin Seed Oil 
(19) 1. Nutr Res Rev. 2010 Dec;23(2):184-90. doi: 10.1017/S0954422410000107.

Medicinal and biological potential of pumpkin: an updated review. http://www.ncbi.nlm.nih.gov/pubmed/21110905

Yadav M(1), Jain S, Tomar R, Prasad GB, Yadav H.

(1)School of Studies in Chemistry, Jiwaji University, Gwalior 474011, M.P., India.
PMID: 21110905 [PubMed – indexed for MEDLINE]

Long Pepper Extract 
(20) Bioavailability enhancers of herbal origin: An overview

Kritika Kesarwani and Rajiv Gupta*
Department of Pharmacognosy, Faculty of Pharmacy, Babu Banarasi Das National Institute of Technology and Management (BBD University), BBD Green City, Lucknow, U.P., 227105, India
Reviewed by Dr. Alok Mukerjee, (M.Pharm.,Ph.D.)
http://www.ncbi.nlm.nih.gov/pubmed/23620848

Vitamin B-5 (Pantothenic Acid)
(21) Y. M. Kuo, S. J. Hayflick, and J. Gitschier (June 2007). “Deprivation of pantothenic acid elicits a movement disorder and azoospermia in a mouse model of pantothenate kinase-associated neurodegeneration”. J Inherit Metab Dis. 30 (3): 310–317. doi:10.1007/s10545-007-0560-8. PMC 2099457. PMID 17429753. http://link.springer.com/article/10.1007%2Fs10545-007-0560-8

Iron 
(22) J Korean Med Sci. 2013 Jun;28(6):934-8. doi: 10.3346/jkms.2013.28.6.934. Epub 2013 Jun 3.
Iron plays a certain role in patterned hair loss.
Park SY1, Na SY, Kim JH, Cho S, Lee JH
Joncyzk R, Ronconi S, Rychlik M, Genschel U. Pantothenate synthetase is essential but not limiting for pantothenate biosynthesis in Arabidopsis. Plant Mol Biol. 2008;66(1-2):1-14. Konings EJ; Committee on Food Nutrition. Water-soluble vitamins. JAOAC Int. 2006 Jan-Feb;89(1):285-8
http://www.ncbi.nlm.nih.gov/pubmed/12190640

(23) Clin Exp Dermatol. 2002 Jul;27(5):396-404.
Nutritional factors and hair loss.
Rushton DH.
Author information: School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth, UK.
http://www.ncbi.nlm.nih.gov/pubmed/12190640

General 
(24) Bown. D. Encyclopaedia of Herbs and their Uses. Dorling Kindersley, London. 1995 ISBN 0-7513-020-31.

(25) Chevallier. A.The Encyclopedia of Medicinal Plants. Dorling Kindersley, London 1996 ISBN 9-780751-303148.